Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep661 | Pituitary: basic and neuroendocrinology | ECE2015

Long-term follow-up of cranially irradiated childhood leukaemia survivors show cognitive impairment and progressive decline in sustained attention, in spite of on complete hormone replacement

Follin Cecilia , Johansson Aki , Osterberg Kai , Rovira Andrea , Jansson Magdalena , Wiebe Thomas , Erfurth Eva Marie

Background: Survivors of childhood leukaemia (ALL) treated with cranial radiotherapy (CRT) are at risk for cognitive impairment. Whether the impairment progresses with follow-up time and if survivors with cognitive impairment have an increased risk for overweight, is unknown. We aimed to investigate the long-term cognitive functioning in ALL survivors treated with CRT in comparison to matched controls.Method: Cognitive functioning was investigated in 38 ...

ea0022p637 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Rapid bone loss 23 years after diagnosis for childhood acute lymfoblastic leukaemia (ALL) in spite of GH therapy

Follin Cecilia , Link Katarina , Wiebe Thomas , Moell Christian , Bjork Jonas , Erfurth Eva Marie

Context: Acute lymphoblastic leukaemia (ALL) is the most common pediatric malignancy and its treatment includes many known risk factors for low bone mineral density (BMD), e.g. glucocorticosteroids, methotrexat and cranial radiotherapy (CRT).Objective: To evaluate bone mineral density (BMD) and markers of bone turn over in a group of adults with childhood onset ALL, treated with CRT and to evaluate the effect of 5 years with, and 8 years without GH thera...